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Home Surgery Knee Cartilage cell transplantation

Cartilage cell transplantation

In the case of cartilage transplantation or cartilage cell or chondrocyte transplantation is a novel surgical procedure, the cartilage defects with the help of the body's own cartilage cells to repair. It is from a few selected specialists in Germany carried out successfully. Dr. Baum was the first physician worldwide to the purely arthroscopic cartilage transplantation has. He has developed this method with other forms and doctors in this surgery technique.



Because of the damaged place in the original joint cartilage tissue nachwächst is the first time a complete healing of cartilage defects is possible.

First, in a small surgery, minimally invasive cartilage cells is being carried out by mechanically loaded bodies not removed. With special refrigerated transport containers, these cells then in a special laboratory.

They are bred and propagated. The cells are first to 3-dimensional beads together the once with the prepared defect bearing contact their 'Connection molecules' (Adhäsionsproteine) exit and after about 10 minutes mechanically stable on the bone attached. As a result, grow the cartilage cells in the defect, until this is completed. This technique can now cartilage defects in the knee, ankle and hip joints fully arthroscopic therapy.
cartilage transplantation animation
How does the cartilage transplant?


Since the implanted material has similar biomechanical properties as the natural cartilage has, it is not absorbed by the body sees as foreign. The living chondrocytes are in a position again for the establishment of a functioning cartilage layer them. Since the spherical shape in cultured cartilage cells (called spheroids) in a second step directly to the body in the joints are damaged, in which the cartilage is missing mass, multiply it directly where the cartilage is needed in the body further. It is the body's own healthy cartilage tissue, all of the protective functions again met with the injured joints have lacked.

What happens after surgery?

Already after about six weeks is a complete covering of the defect with living cartilage cells, but not yet the thickness and resilience of the surrounding cartilage possess. Like a freshly converted lawn on which to protect the young plants will not immediately football should be played, should at this time walking sticks are used for discharge. At the same time is at a sufficient movement of the joint to be ensured so that the pressure change of the circulation is stimulated. The nutrition of the cartilage takes place by diffusion - like a sponge. If the pressed together, so the slag ausgeschwemmt substances, in contrast, the discharge will be recorded Nährsubstanzen. Special tracks movement and physiotherapy support the healing.

When can again be burdened?

After about six weeks should be part of the burden started after more than three months to walking sticks to be waived.

When can again be sporting?

Cycling and swimming, and the other joint-friendly sports for about three months is recommended. After complete regeneration of the cartilage defect, about a year after the operation, is full of new cartilage Einheilung completed and the joint is fully loaded and ready for all sports.

Who benefits from this method?

Not always, the cartilage transplantation into consideration. When the articular defect is too large, or the opposite surface is also heavily damaged, it is to late.

Prerequisite for successful cartilage transplant is a very stable joint, a normal joint axis and the absence of free joint body, which could jeopardize the graft.

Typical indications for the transplantation of cartilage cells (chondrocytes) are local articular cartilage defects in the knee or particularly ankle. Ideal conditions for the transplant in a patient aged 15 - 55 years, a defect size to 10 square centimeters, while the presence of healthy cartilage, where the rest. The knee should be stable, ie the ligaments intact. Unusual strains of joints such as significant obesity should be avoided whenever possible.

Generally, this method only until age 55ten recommended, is the critical biological, not the calendar age of the patients.


knorpeltransplantation_ersatz_knorpel_erfolgreich

Main defect 1 year after the surgery


Benefits at a glance:

  • Pain reduction
  • Restoration of resilience
  • improved agility
  • Reconstruction of the cartilage layer
  • Prevention of joint replacement

knorpelzellen_chondrosphroide

Inclusion of spheroids - bred
from the body's own cartilage cells, each with
82,000 cells per ball


Last Updated ( Thursday, 11 August 2011 14:11 )  

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